Sitting too long makes you fat, age faster


23 January, 2017

Telomere length was measured from DNA in blood cells. Although shortened telomeres have been linked to certain diseases, everyone's telomeres shorten over time.

Researchers evaluated the link between leukocyte telomere length (LTL) and sedentary time in 1,481 older women, who were either white or African-American, from the Women's Health Initiative - a cross-sectional, longitudinal study from 2012-2013, which examined the factors that determine chronic diseases in postmenopausal women. Furthermore, other conditions, such as diabetes, heart disease, and cancers, might accelerate the degeneration.

The findings were published in the American Journal of Epidemiology. "Therefore, it is possible that women who spend long hours sedentary coupled with less time in (moderate to vigorous physical activity) may not be exposed to these antioxidant and anti-inflammatory defenses".

The new study was performed by a team of scientists from the San Diego's School of Medicine (University of California) led by Aladdin Shadyab.

The sedentary time was assessed using both self-reporting and an accelerometer.

The researchers carried out a lot of comparisons and used multiple models to try to show sedentary time was linked to telomere length. For the duration of the project (approximately one week), the participants were asked to wear a special monitor and to complete a series of questionnaires pertaining to their daily habits. Women were aged 79.2 (standard deviation, 6.7) years, on average. "Women who did not meet the physical activity guideline and were sedentary for at least 10 hours a day were biologically older; their cells are aging faster than those of women who were less sedentary".

Eli Lilly buys Massachusetts-based pharmaceuticals company for $960 million
Shares of LLY are now unchanged to start the beginning of shortened trading week following the Martin Luther King Jr. holiday. A number of analysts offered their Estimated Earnings analysis for Eli Lilly and Company (NYSE:LLY) for the current quarter.

Putin: Donald Trump's political enemies 'worse than prostitutes'
The Russians replied tit-for-tat; they expelled 35 USA diplomats and closed two US compounds operating near Moscow. "Five. Trump personally, I have never met him and don't know what he will do on the worldwide arena.

Obama fetes world-champion Chicago Cubs, his (wife's) favorite
He joked with Theo Epstein about becoming the chairperson of the Democratic National Party . - "It took you long enough". Chicago Cubs president Theo Epstein on Monday "pardoned" Obama for supporting the Chicago White Sox for all these years.

Specifically, low physical activity seemed to account for an 8-year biological age gap between those who exercised and those who did not. The chronological age of a person doesn't always match the person's biological age. But Shadyab's study shows that sedentary behavior has potentially aging effects on the cells, and exercise may be one way to combat that aging process.

According to Shadyab, this is the first time that a study has investigated the link between sedentary time, exercise, and telomeres. The researchers found that the ends of their DNA strands known as telomeres are shorter than normal-this structure is known to providing protection to chromosomes against deterioration and shortening associated with age.

They also acknowledged women who have long-term illnesses are more likely to have a sedentary lifestyle, and the illness rather than the lack of exercise may cause shortened telomeres.

"Discussions about the benefits of exercise should start when we are young, and physical activity should continue to be part of our daily lives as we get older, even at 80 years old", he advised.

Shadyab also added that future studies will look at how exercise could affect telomere length in younger populations and in men.

More news

  • Trump Fires Back At CIA Chief On Twitter

    Friction between U.S. intelligence agencies and presidents is not new but has never been played out so publicly. He suggested Brennan might be " the leaker of Fake News ".

    Dozens of false killer whales stranded off South Florida

    No boats or flyovers are allowed near the scene as the National Park Service has closed off the area for safety reasons. In the early 1990s, a survey counted almost 400 in the northern Gulf of Mexico with just over 1,000 estimated globally.
    Andy Carroll scores incredible overhead kick in West Ham vs. Crystal Palace

    Andy Carroll scores incredible overhead kick in West Ham vs. Crystal Palace

    Indeed, West Ham actually put on their best display of the season while their so-called talisman kicked his heels elsewhere. It's a massive club and he is absolutely adored - was adored - by the fans, but football and fans change quickly".
  • Six surprising provisions that could disappear with ACA repeal

    CNN reports that the act does not itself change the law; it allows parts of the ACA to be loosened before Congress can fully repeal it.
    Trump talked to husband of slain Orlando officer

    Trump talked to husband of slain Orlando officer

    The judge said Thursday that Loyd would have a hearing in one week to determine counsel for him in the case over Dixon's death. As Clayton was on the radio with the dispatcher, three gunshots could be heard and the call went dead, investigators said.

    Rhode Island sisters abducted as children found 31 years later in Houston

    Elaine Yates was being taken back to Rhode Island, where she will face arraignment Wednesday in Kent Superior Court in Warwick. Last month, Rhode Island State Police said they received a tip about the whereabouts of the mother and her daughters.
  • Johanna Konta "Looking Forward To The Challenge" of Caroline Wozniacki

    Konta said of Osaka, "She is one of the up and coming players and she's had some really impressive results over the last 12 months or so".

    North Korea may be readying missile test, timing unclear

    North Korea may launch an intercontinental ballistic missile in the "near future", South Korean media reports . North Korea has defiantly continued its nuclear-weapons development, despite sanctions and global outcry.
    Australia vs Pakistan 2nd ODI: Hafeez's 72 brings Pakistan level

    Australia vs Pakistan 2nd ODI: Hafeez's 72 brings Pakistan level

    Though Pakistan were not required to score huge runs, they lost wickets at regular intervals, which led to their downfall. Glenn Maxwell managed to make an encouraging 23 before he was cleaned up by Imad Wasim.
  • Watch Bernie Sanders and Elizabeth Warren School Trump's Education Secretary Pick

    Department of Education, has a odd way of demonstrating the animosity toward gay people she is being accused by some of harboring. DeVos has also fought to expand school vouchers, virtual schools, tuition tax credits and education savings accounts.

    China urges the U.S. to stop Taiwanese delegation from attending Trump's inauguration

    Taiwan is the US' ninth-largest trading partner, and the United States is Taiwan's second-largest, the US State Department says. Taiwan is to send Yu Shyi-kun, former premier and ex-ruling party leader, to represent Taipei at Trump's inauguration.

    Eight Dudes Are As Rich As Half Of The World

    Obscenely rich, if a new report by Oxfam , an worldwide confederation of charitable organisations, is to be believed. Mark Zuckerberg: American chairman, chief executive officer, and co-founder of Facebook (net worth $44.6 billion) 7.